The Mother of All Cannabinoids: CBG


Ingredients matter – that’s why you read the nutrition label while eating your favourite snack. and It’s also why we’ve purposefully chosen just the right ingredients for the best experience possible with the Buddy Homburg Modern Infused Cannagar. The Ingredient we are most excited about is CBG (cannabigerol), a minor cannabinoid that will leave you wanting more – here’s why:

What is CBG?

Non-psychoactive CBG is one of many cannabinoids sourced from the cannabis plant. It has long been called “the Mother of all cannabinoids” because its acidic form (CBGa) is the building block for other cannabinoids such as CBG, CBD, THC and CBC. With this pedigree, it’s not really accurate to call it a minor now, is it?

How CBG works

CBG, like other cannabinoids, binds to a person’s CB1 and CB2 receptors in the endocannabinoid system and reaches its destination through ingestion, inhalation, or application to the skin. When this happens, it is thought to optimize the function of the neurotransmitter, anandamide – which increases motivation and pleasure, regulates appetite and sleep, plus alleviates pain.

It’s no wonder anecdotal evidence points to increased potency of effects when CBD is stacked with other cannabinoids and terpenes. 

CBG is to awake what CBN is to asleep

CBN is becoming known as nature’s sleep aid, but could CBG be nature’s energy drink? Early research, studies and anecdotal evidence suggest that CBG may offer us a suite of impactful cognitive benefits, thanks to the effect it has on the anandamide. Improved sense of alertness, focus and mood, along with a reduction of stress and chronic discomfort may be experienced from CBG.

Take your time

It’s the Homburg way.

A single dose of CBG may reduce the resting blood pressure response to stress. High blood pressure can cause headaches, dizziness, shortness of breath, nosebleeds, etc.  Some evidence suggests that CBG activates alpha2-adrenoreceptors, which effect blood pressure. CBG also binds to the 5-HT1A to inhibit serotonin uptake, which may improve mood and may have anxiolytic (anxiety reducing) effects.

Time to soothe

Early research on airway inflammation suggests CBG and CBD, alone and combined, exhibit anti-inflammatory effects. CBG aids with inflammation by reducing lipopolysaccharides (LPS) induced recruitment of neutrophils into the lung. Neutrophils are a type of white blood cell – and signify infection and inflammation.

Bacteria be gone

With inflammation, sometimes comes bacteria. Welcome to 2022 – bacteria is gross again and antibacterial products are most welcome. CBG may serve as a promising natural antibacterial. Research shows that is effective against gram-positive bacteria – specifically s. mutans (strep).

Time to celebrate CBG

We’re impressed too – Anecdotal evidence and early research on CBG point to a myriad of additional purported benefits that we haven’t even begun to cover, and research is growing (pun intended) in the cannabis industry as cannabis legalization continues to spread and education becomes more easily accessible to consumers.

Always celebrate with a Buddy.

Koslow, T. 2019: ‘What is CBG? The minor cannabinoid with major potential, explained’, Journal of Cannabinoid Medicine 2019
Jadoon, K. et al 2017: ‘A single dose of cannabidiol reduces bood pressure in healthy volunteers in a randomized crossover study’, JCI insight 2017
Farha, M. et al 2020: ‘Uncovering the hidden antibiotic potential of cannabis’, ACS Infect. Dis. 2020
Cabrera C. et al 2021: ‘The anti-inflammatory effects of cannabidiol and cannabigerol alone, and in combination’. Pulm Pharmacol Ther. 2021

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